Thermo-Tunable Pores and Antibiotic Gating Properties of Bovine Skin Gelatin Gels 

Thermo-Tunable Pores and Antibiotic Gating Properties of Bovine Skin Gelatin Gels 

Publicity to a Manuka Honey Wound Gel Is Related With Adjustments in Bacterial Virulence and Antimicrobial Susceptibility

Using manuka honey for the topical therapy of wounds has elevated worldwide owing to its broad spectrum of exercise in the direction of micro organism in each planktonic and biofilm development modes. Regardless of this, the potential penalties of bacterial publicity to manuka honey, as could happen through the therapy of persistent wounds, will not be absolutely understood.

Right here, we describe adjustments in antimicrobial susceptibility and virulence in a panel of micro organism, together with wound isolates, following repeated publicity (ten passages) to sub-inhibitory concentrations of a manuka honey primarily based wound gel. Adjustments in antibiotic sensitivity above 4-fold had been predominantly associated to elevated vancomycin sensitivity within the staphylococci.

Curiously, Staphylococcus epidermidis displayed phenotypic resistance to erythromycin following passaging, with susceptibility profiles returning to baseline within the absence of additional honey publicity. Adjustments in susceptibility to the examined wound gel had been average (≤ 1-fold) when in comparison with the respective guardian pressure.

In sessile communities, elevated biofilm eradication concentrations over 4-fold occurred in a wound isolate of Pseudomonas aeruginosa (WIBG 2.2) as evidenced by a 7-fold discount in gentamicin sensitivity following passaging. On the subject of pathogenesis, 4/eight micro organism exhibited enhanced virulence following honey wound gel publicity. Within the pseudomonads and S. epidermidis, this occurred together with elevated haemolysis and biofilm formation, while P. aeruginosa additionally exhibited elevated pyocyanin manufacturing.

The place virulence attenuation was famous in a passaged wound isolate of S. aureus (WIBG 1.6), this was concomitant to delayed coagulation and decreased haemolytic potential. Total, passaging within the presence of a manuka honey wound gel led to adjustments in antimicrobial sensitivity and virulence that various between take a look at micro organism.

soveinc
soveinc

Gelsolin (GS) Antibody

20-abx132379
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Gelsolin (GS) Antibody (FITC)

20-abx274147
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Gelsolin (GS) Antibody Pair

20-abx370115
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Gelsolin (GS) Antibody Pair

20-abx370757
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Gelsolin (GS) Antibody Pair

20-abx370810
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Gelsolin (GS) Antibody (Biotin)

20-abx271800
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Gelsolin (GS) Antibody (Biotin)

20-abx273100
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Gelsolin (GS) Polyclonal Antibody (Rat)

4-PAA372Ra01
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Description: A Rabbit polyclonal antibody against Rat Gelsolin (GS)

Gelsolin (GS) Monoclonal Antibody (Human)

4-MAA372Hu22
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Description: A Mouse monoclonal antibody against Human Gelsolin (GS)

Gelsolin (GS) Polyclonal Antibody (Human)

4-PAA372Hu01
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS)

Gelsolin (GS) Polyclonal Antibody (Human)

4-PAA372Hu02
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS)

Gelsolin (GS) Polyclonal Antibody (Human)

4-PAA372Hu03
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS)

Gelsolin (GS) Polyclonal Antibody (Human)

4-PAA372Hu04
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS)

Gelsolin (GS) Monoclonal Antibody (Bovine)

4-MAA372Bo21
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Description: A Mouse monoclonal antibody against Bovine Gelsolin (GS)

Gelsolin (GS) Polyclonal Antibody (Bovine)

4-PAA372Bo01
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Description: A Rabbit polyclonal antibody against Bovine Gelsolin (GS)

Gelsolin (GS) Polyclonal Antibody (Rat), PE

4-PAA372Ra01-PE
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Description: A Rabbit polyclonal antibody against Rat Gelsolin (GS). This antibody is labeled with PE.

Gelsolin (GS) Polyclonal Antibody (Rat), APC

4-PAA372Ra01-APC
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Description: A Rabbit polyclonal antibody against Rat Gelsolin (GS). This antibody is labeled with APC.

Gelsolin (GS) Polyclonal Antibody (Rat), Cy3

4-PAA372Ra01-Cy3
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Description: A Rabbit polyclonal antibody against Rat Gelsolin (GS). This antibody is labeled with Cy3.

Gelsolin (GS) Polyclonal Antibody (Rat), HRP

4-PAA372Ra01-HRP
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Description: A Rabbit polyclonal antibody against Rat Gelsolin (GS). This antibody is labeled with HRP.

Gelsolin (GS) Monoclonal Antibody (Human), PE

4-MAA372Hu22-PE
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Description: A Mouse monoclonal antibody against Human Gelsolin (GS). This antibody is labeled with PE.

Gelsolin (GS) Polyclonal Antibody (Human), PE

4-PAA372Hu01-PE
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with PE.

Gelsolin (GS) Polyclonal Antibody (Human), PE

4-PAA372Hu02-PE
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with PE.

Gelsolin (GS) Polyclonal Antibody (Human), PE

4-PAA372Hu03-PE
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with PE.

Gelsolin (GS) Polyclonal Antibody (Human), PE

4-PAA372Hu04-PE
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with PE.

Gelsolin (GS) Polyclonal Antibody (Rat), FITC

4-PAA372Ra01-FITC
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Description: A Rabbit polyclonal antibody against Rat Gelsolin (GS). This antibody is labeled with FITC.

anti- Gelsolin antibody

FNab03417 100µg
EUR 606.3
Description: Antibody raised against Gelsolin

Gelsolin (GS) Monoclonal Antibody (Bovine), PE

4-MAA372Bo21-PE
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Description: A Mouse monoclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with PE.

Gelsolin (GS) Monoclonal Antibody (Human), APC

4-MAA372Hu22-APC
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Description: A Mouse monoclonal antibody against Human Gelsolin (GS). This antibody is labeled with APC.

Gelsolin (GS) Monoclonal Antibody (Human), Cy3

4-MAA372Hu22-Cy3
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Description: A Mouse monoclonal antibody against Human Gelsolin (GS). This antibody is labeled with Cy3.

Gelsolin (GS) Monoclonal Antibody (Human), HRP

4-MAA372Hu22-HRP
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Description: A Mouse monoclonal antibody against Human Gelsolin (GS). This antibody is labeled with HRP.

Gelsolin (GS) Polyclonal Antibody (Bovine), PE

4-PAA372Bo01-PE
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Description: A Rabbit polyclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with PE.

Gelsolin (GS) Polyclonal Antibody (Human), APC

4-PAA372Hu01-APC
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with APC.

Gelsolin (GS) Polyclonal Antibody (Human), Cy3

4-PAA372Hu01-Cy3
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with Cy3.

Gelsolin (GS) Polyclonal Antibody (Human), HRP

4-PAA372Hu01-HRP
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with HRP.

Gelsolin (GS) Polyclonal Antibody (Human), APC

4-PAA372Hu02-APC
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with APC.

Gelsolin (GS) Polyclonal Antibody (Human), Cy3

4-PAA372Hu02-Cy3
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with Cy3.

Gelsolin (GS) Polyclonal Antibody (Human), HRP

4-PAA372Hu02-HRP
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with HRP.

Gelsolin (GS) Polyclonal Antibody (Human), APC

4-PAA372Hu03-APC
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with APC.

Gelsolin (GS) Polyclonal Antibody (Human), Cy3

4-PAA372Hu03-Cy3
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with Cy3.

Gelsolin (GS) Polyclonal Antibody (Human), HRP

4-PAA372Hu03-HRP
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with HRP.

Gelsolin (GS) Polyclonal Antibody (Human), APC

4-PAA372Hu04-APC
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with APC.

Gelsolin (GS) Polyclonal Antibody (Human), Cy3

4-PAA372Hu04-Cy3
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with Cy3.

Gelsolin (GS) Polyclonal Antibody (Human), HRP

4-PAA372Hu04-HRP
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with HRP.

Gelsolin (GS) Monoclonal Antibody (Bovine), APC

4-MAA372Bo21-APC
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Description: A Mouse monoclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with APC.

Gelsolin (GS) Monoclonal Antibody (Bovine), Cy3

4-MAA372Bo21-Cy3
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Description: A Mouse monoclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with Cy3.

Gelsolin (GS) Monoclonal Antibody (Bovine), HRP

4-MAA372Bo21-HRP
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Description: A Mouse monoclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with HRP.

Gelsolin (GS) Monoclonal Antibody (Human), FITC

4-MAA372Hu22-FITC
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Description: A Mouse monoclonal antibody against Human Gelsolin (GS). This antibody is labeled with FITC.

Gelsolin (GS) Polyclonal Antibody (Bovine), APC

4-PAA372Bo01-APC
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Description: A Rabbit polyclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with APC.

Gelsolin (GS) Polyclonal Antibody (Bovine), Cy3

4-PAA372Bo01-Cy3
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Description: A Rabbit polyclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with Cy3.

Gelsolin (GS) Polyclonal Antibody (Bovine), HRP

4-PAA372Bo01-HRP
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Description: A Rabbit polyclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with HRP.

Gelsolin (GS) Polyclonal Antibody (Human), FITC

4-PAA372Hu01-FITC
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with FITC.

Gelsolin (GS) Polyclonal Antibody (Human), FITC

4-PAA372Hu02-FITC
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with FITC.

Gelsolin (GS) Polyclonal Antibody (Human), FITC

4-PAA372Hu03-FITC
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with FITC.

Gelsolin (GS) Polyclonal Antibody (Human), FITC

4-PAA372Hu04-FITC
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with FITC.

Gelsolin (GS) Monoclonal Antibody (Bovine), FITC

4-MAA372Bo21-FITC
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Description: A Mouse monoclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with FITC.

Gelsolin (GS) Polyclonal Antibody (Bovine), FITC

4-PAA372Bo01-FITC
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Description: A Rabbit polyclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with FITC.

Gelsolin (GS) Polyclonal Antibody (Human, Mouse)

4-PAA372Mu01
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Description: A Rabbit polyclonal antibody against Human, Mouse Gelsolin (GS)

Gelsolin (GS) Polyclonal Antibody (Rat), Biotinylated

4-PAA372Ra01-Biotin
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Description: A Rabbit polyclonal antibody against Rat Gelsolin (GS). This antibody is labeled with Biotin.

Gelsolin (GS) Monoclonal Antibody (Human), Biotinylated

4-MAA372Hu22-Biotin
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  • 100ul
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Description: A Mouse monoclonal antibody against Human Gelsolin (GS). This antibody is labeled with Biotin.

Gelsolin (GS) Polyclonal Antibody (Human), Biotinylated

4-PAA372Hu01-Biotin
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with Biotin.

Gelsolin (GS) Polyclonal Antibody (Human), Biotinylated

4-PAA372Hu02-Biotin
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with Biotin.

Gelsolin (GS) Polyclonal Antibody (Human), Biotinylated

4-PAA372Hu03-Biotin
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with Biotin.

Gelsolin (GS) Polyclonal Antibody (Human), Biotinylated

4-PAA372Hu04-Biotin
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with Biotin.

Gelsolin (GS) Polyclonal Antibody (Rat), APC-Cy7

4-PAA372Ra01-APC-Cy7
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Description: A Rabbit polyclonal antibody against Rat Gelsolin (GS). This antibody is labeled with APC-Cy7.

Gelsolin (GS) Monoclonal Antibody (Bovine), Biotinylated

4-MAA372Bo21-Biotin
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Description: A Mouse monoclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with Biotin.

Gelsolin (GS) Polyclonal Antibody (Bovine), Biotinylated

4-PAA372Bo01-Biotin
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Description: A Rabbit polyclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with Biotin.

Gelsolin (GS) Polyclonal Antibody (Human, Mouse), PE

4-PAA372Mu01-PE
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Description: A Rabbit polyclonal antibody against Human, Mouse Gelsolin (GS). This antibody is labeled with PE.

Gelsolin (GS) Monoclonal Antibody (Human), APC-Cy7

4-MAA372Hu22-APC-Cy7
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Description: A Mouse monoclonal antibody against Human Gelsolin (GS). This antibody is labeled with APC-Cy7.

Gelsolin (GS) Polyclonal Antibody (Human), APC-Cy7

4-PAA372Hu01-APC-Cy7
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Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with APC-Cy7.

Gelsolin (GS) Polyclonal Antibody (Human), APC-Cy7

4-PAA372Hu02-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with APC-Cy7.

Gelsolin (GS) Polyclonal Antibody (Human), APC-Cy7

4-PAA372Hu03-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with APC-Cy7.

Gelsolin (GS) Polyclonal Antibody (Human), APC-Cy7

4-PAA372Hu04-APC-Cy7
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  • 100ul
  • 10ml
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  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Gelsolin (GS). This antibody is labeled with APC-Cy7.

Gelsolin (GS) Polyclonal Antibody (Human, Mouse), APC

4-PAA372Mu01-APC
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  • 100ul
  • 10ml
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Description: A Rabbit polyclonal antibody against Human, Mouse Gelsolin (GS). This antibody is labeled with APC.

Gelsolin (GS) Polyclonal Antibody (Human, Mouse), Cy3

4-PAA372Mu01-Cy3
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human, Mouse Gelsolin (GS). This antibody is labeled with Cy3.

Gelsolin (GS) Polyclonal Antibody (Human, Mouse), HRP

4-PAA372Mu01-HRP
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human, Mouse Gelsolin (GS). This antibody is labeled with HRP.

Gelsolin (GS) Monoclonal Antibody (Bovine), APC-Cy7

4-MAA372Bo21-APC-Cy7
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  • 100ul
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Description: A Mouse monoclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with APC-Cy7.

Gelsolin (GS) Polyclonal Antibody (Bovine), APC-Cy7

4-PAA372Bo01-APC-Cy7
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  • 100ul
  • 10ml
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Description: A Rabbit polyclonal antibody against Bovine Gelsolin (GS). This antibody is labeled with APC-Cy7.

Gelsolin (GS) Polyclonal Antibody (Human, Mouse), FITC

4-PAA372Mu01-FITC
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  • 100ul
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Description: A Rabbit polyclonal antibody against Human, Mouse Gelsolin (GS). This antibody is labeled with FITC.

Recombinant Gelsolin (GS)

4-RPA372Bo01
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  • 100 ug
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  • 1 mg
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  • 5 mg
Description: Recombinant Bovine Gelsolin expressed in: E.coli

Recombinant Gelsolin (GS)

4-RPA372Hu01
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  • 100 ug
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  • 5 mg
Description: Recombinant Human Gelsolin expressed in: E.coli

Recombinant Gelsolin (GS)

4-RPA372Hu02
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  • 100 ug
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  • 1 mg
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  • 5 mg
Description: Recombinant Human Gelsolin expressed in: E.coli

Recombinant Gelsolin (GS)

4-RPA372Hu03
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  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Gelsolin expressed in: E.coli

Recombinant Gelsolin (GS)

4-RPA372Hu04
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  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Gelsolin expressed in: E.coli

Recombinant Gelsolin (GS)

4-RPA372Mu01
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  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Gelsolin expressed in: E.coli

Recombinant Gelsolin (GS)

4-RPA372Ra01
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  • 100 ug
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  • 50ug
  • 5 mg
Description: Recombinant Rat Gelsolin expressed in: E.coli

Gelsolin antibody

10-1754 200 ul
EUR 1972
Description: Mouse monoclonal Gelsolin antibody

Gelsolin antibody

10R-7858 100 ug
EUR 514
Description: Mouse monoclonal Gelsolin antibody

Gelsolin antibody

10R-8459 100 ul
EUR 471.6
Description: Mouse monoclonal Gelsolin antibody

Gelsolin Antibody

E19-7711-1 50ug/50ul
EUR 145
Description: Available in various conjugation types.

Gelsolin Antibody

E19-7711-2 100ug/100ul
EUR 225
Description: Available in various conjugation types.

Thermo-Tunable Pores and Antibiotic Gating Properties of Bovine Pores and skin Gelatin Gels Ready with Poly(n-isopropylacrylamide) Community

Polystyrene nanospheres (PNs) had been embedded in bovine pores and skin gelatin gels with a poly(N-isopropylacrylamide) (PNIPAAm) community, which had been denoted as NGHHs, to generate thermoresponsive habits. When 265 nm PNs had been exploited to generate the pores, bovine pores and skin gelatin prolonged to utterly occupy the pores left by PNs beneath the decrease vital answer temperature (LCST), forming a pore-less construction.

Contrarily, above the LCST, the collapse of hydrogen bonding between bovine pores and skin gelatin and PNIPAAm occurred, leading to pores within the NGHH. The habits of pore closing and opening beneath and above the LCST, respectively, signifies the superb drug gating effectivity.

Amoxicillin (AMX) was loaded into the NGHHs as sensible antibiotic gating as a result of pore closing and opening habits. Accordingly, E. coli. and S. aureus had been exploited to check the micro organism inhibition ratio (BIR) of the AMX-loaded NGHHs. BIRs of NGHH with out pores had been 48% to 46.7% at 25 and 37 °C, respectively, for E. coli throughout 12 h of incubation time.

The BIRs of nanoporous NGHH could possibly be enhanced from 61.5% to 90.4% offering a wise antibiotic gate of bovine pores and skin gelatin gels in opposition to irritation from an infection or harm irritation.

Discrimination of extremely degraded, aged Asian and African elephant ivory utilizing denaturing gradient gel electrophoresis (DGGE)

Background: Elephant populations have vastly decreased primarily on account of unlawful poaching for his or her ivory. The commerce in elephant merchandise is protected by nationwide legal guidelines and CITES agreements to stop them from additional decline. For example, in Thailand, it’s unlawful to commerce ivory from African elephants; nonetheless, the legislation permits possession of ivory from Asian elephants if permission has been obtained from the authorities.

As such, technique of enforcement of laws are wanted to categorise the authorized standing of seized ivory merchandise. Many DNA-based methods have been beforehand reported for this function, though all have a restrict of detection not appropriate for very degraded samples.

Intention: We report an assay primarily based on nested PCR adopted by DGGE to substantiate the authorized or unlawful standing of seized ivory samples the place it’s assumed that the DNA can be extremely degraded.

Technique and outcomes: The assay was examined on aged ivory from which the assay was examined for reproducibility, specificity, and, importantly, sensitivity. Blind testing confirmed 100% identification accuracy. Appropriate task in all 304 samples examined was achieved together with affirmation of the authorized standing of 227 extremely degraded, aged ivories, thus underlining the excessive sensitivity of the assay.

Conclusion and suggestion: The analysis output can be helpful to research ivory casework samples in wildlife forensic laboratories.

Results of Emicizumab on APTT, FVIII assays and FVIII Inhibitor assays utilizing completely different reagents: Outcomes of a UK NEQAS proficiency testing train

Introduction: Emicizumab (Hemlibra: Roche Switzerland) is a, humanized, bi-specific monoclonal modified immunoglobulin G4 (IgG4) which binds human FX, FIX and activated FIX (FIXa) to imitate activated FVIII exercise.

Intention: Consider the consequences of emicizumab on the APTT, surrogate FVIII exercise and FVIII inhibitor outcomes.

Strategies: Two samples had been offered, one obtained from an emicizumab handled extreme haemophilia A affected person with FVIII inhibitors and one constructed by in vitro addition of emicizumab utilizing plasma from a extreme haemophilia A affected person with out FVIII inhibitors. An APTT display, surrogate FVIII and FVIII inhibitor assessments had been carried out on each samples by collaborating centres.

Outcomes: APTT outcomes had been beneath the decrease restrict of regular vary. Chromogenic FVIII assay outcomes with the Hyphen/Biophen human component-based assay gave larger than anticipated coefficient of variation (CV) outcomes, 38%-40%. The modified one-stage FVIII assay with emicizumab calibrators confirmed comparable outcomes whatever the APTT reagent. Inhibitor assay median outcomes for pattern S18:23 = 1.43 BU (vary 0.9-3.Zero BU/ml, CV 38%). S18:24 was categorized as beneath the decrease restrict of detection.

Conclusion: APTT screens confirmed a constant shortening. Unmodified one-stage Issue VIII assay outcomes had been remarkably excessive. APTT-based assays are unsuitable for measurement of coagulation components or inhibitors in sufferers handled with emicizumab. Bovine origin chromogenic assays are insensitive to emicizumab and ought to be used to observe FVIII ranges/FVIII inhibitors in emicizumab handled sufferers. Product-specific calibrators ought to be carried out to scale back end result variability.

 

Identification of Immunohistochemical Reagents for In Situ Protein Expression Evaluation of Coronavirus-associated Adjustments in Human Tissues

We studied the suitability of commercially out there monoclonal antibodies (mAbs) for the immunohistochemical (IHC) detection of extreme acute respiratory syndrome coronavirus 2 (SARS-CoV2) in customary archival specimens. Antibodies had been screened on HEK293 cells transfected with viral nucleoprotein, S1 subunit and S2 subunit of spike protein and on untransfected cells, in addition to a panel of regular tissue.

Lung tissue with presence of SARS-CoV2 confirmed by in situ hybridization (ISH) was additionally used. A complete of seven mAbs had been examined: (1) mAb 001 (Sino Organic, 40143-R001), (2) mAb 007 (Sino Organic, 40150-R007), (3) mAb 019 (Sino Organic, 40143-R019), (4) mAb 1A9 (GeneTex, GTX632604), (5) mAb ABM19C9 (Abeomics, 10-10007), (6) FIPV3-70 (Santa Cruz, SC-65653), and (7) mAb 6F10 (BioVision, A2060). Solely 2 mAbs, clone 001 to the nucleoprotein and clone 1A9 to the S2 subunit spike protein displayed particular immunoreactivity.

Each clones confirmed sturdy staining within the acute part of COVID-19 pneumonia, largely in areas of acute diffuse alveolar injury, however weren’t utterly congruent. Viral protein was additionally present in kidney tubules, endothelia of a number of organs and a nasal swab of a affected person with persistent SARS-CoV2 an infection.

GFP expression Adenovirus, in vivo ready

AVP011-PBS 1x1011 IFU/ml x 50ul
EUR 852
Description: pre-made GFP expression adenovirus, provided in PBS solution.

YFP expression Adenovirus, in vivo ready

AVP012-PBS 1x1011 IFU/ml x 50ul
EUR 852
Description: pre-made YFP expression adenovirus, provided in PBS solution.

BFP expression Adenovirus, in vivo ready

AVP017-PBS 1x1011 IFU/ml x 50ul
EUR 852
Description: pre-made BFP expression adenovirus, provided in PBS solution.

EP Reagent Biuret Reagent - 100ML

1011601 1L
EUR 59.4

293 Expression MAX-1

EXP-711-11 1ml
EUR 214
Description: 293 Expression MAX-1 is expressed from - -.

PEROXIDE BLOCKING REAGENT Reagent

GWB-Q00308 50 ml Ask for price

CNGA2 Expression vector

60642 20 µg
EUR 900
Description: The CNGA2 expression vector is designed to express human cyclic nucleotide-gated cation channel 2 (CNGA2) in mammalian cells.

CNGA2 Expression vector

GWB-PSFA61 20ug Ask for price

EP Reagent Iodoplatinate Reagent - 200ML

1046300 200ML
EUR 502.2

EP Reagent Molybdovanadic Reagent - 100ML

1056700 100ML
EUR 59.4

LEXSYcon2.1 Expression Kit

EGE-1310ble 1Kit
EUR 1296.1
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit

EGE-1310bsd 1Kit
EUR 1296.1
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit

EGE-1310hyg 1Kit
EUR 1296.1
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit

EGE-1310neo 1Kit
EUR 1296.1
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit

EGE-1310pac 1Kit
EUR 1296.1
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit

EGE-1310sat 1Kit
EUR 1296.1
Description: for constitutive cytosolic or secretory protein expression

pYLEX1 - Expression Vector

FYY203-5MG 5mg Ask for price

h OCT4 expression Adenovirus, in vivo ready

AVP013-PBS 1x1011 IFU/ml x 50ul
EUR 852
Description: pre-made adenovirus express human stem cell factor, OCT4, provided in PBS solution for in vivo application.

h SOX2 expression Adenovirus, in vivo ready

AVP014-PBS 1x1011 IFU/ml x 50ul
EUR 852
Description: pre-made adenovirus express human stem cell factor, SOX2, provided in PBS solution for in vivo application.

Blunt E1 Expression Kit

abx098098-10rxns 10 rxns
EUR 560.4

Blunt E2 Expression Kit

abx098873-10rxns 10 rxns
EUR 560.4

Blunt E1 Expression Kit

abx098098-100l 100 µl
EUR 712.5

Blunt E1 Expression Kit

abx098098-1ml 1 ml Ask for price

Blunt E1 Expression Kit

abx098098-200l 200 µl Ask for price

Blunt E2 Expression Kit

abx098873-100l 100 µl
EUR 712.5

Blunt E2 Expression Kit

abx098873-1ml 1 ml Ask for price

Blunt E2 Expression Kit

abx098873-200l 200 µl Ask for price

RFP expression Adenovirus

AVP001 1x109 IFU/ml x 200ul
EUR 418.8
Description: pre-made RFP expression adenovirus, provided in DMEM medium.

CFP expression Adenovirus

AVP002 1x109 IFU/ml x 200ul
EUR 418.8
Description: pre-made CFP expression adenovirus, provided in DMEM medium.

GFP expression Adenovirus

AVP011 1x109 IFU/ml x 200ul
EUR 418.8
Description: pre-made GFP expression adenovirus, provided in DMEM medium.

YFP expression Adenovirus

AVP012 1x109 IFU/ml x 200ul
EUR 418.8
Description: pre-made YFP expression adenovirus, provided in DMEM medium.

BFP expression Adenovirus

AVP017 1x109 IFU/ml x 200ul
EUR 418.8
Description: pre-made BFP expression adenovirus, provided in DMEM medium.

h LIN28 expression Adenovirus, in vivo ready

AVP015-PBS 1x1011 IFU/ml x 50ul
EUR 852
Description: pre-made adenovirus express human stem cell factor, LIN28, provided in PBS solution for in vivo application.

LEXSinduce3 Expression Kit

EGE-1410ble 1Kit
EUR 3037.6
Description: for inducible cytosolic or secretory protein expression

LEXSinduce3 Expression Kit

EGE-1410blecherry 1Kit
EUR 3037.6
Description: for inducible cytosolic or secretory protein expression

LEXSinduce3 Expression Kit

EGE-1410neo 1Kit
EUR 3037.6
Description: for inducible cytosolic or secretory protein expression

LEXSinduce4 Expression Kit

EGE-1420blecherry 1Kit
EUR 3037.6
Description: for inducible cytosolic or secretory protein expression

EP Reagent Methoxyphenylacetic Reagent - 100ML

1053601 100ML
EUR 490.05

RPL21_17_477 Over-expression Lysate Product

GWB-8BD971 0.1 mg Ask for price

Rac1 Expression Vector Set

STA-454 1 kit
EUR 1765.2
Description: Rac1 Expression Vector Set contains 3 vectors: Rac wild type, T17N dominant negative mutant, and G12V constitutively active mutant.

RhoA Expression Vector Set

STA-456 1 kit
EUR 1765.2
Description: RhoA Expression Vector Set contains 3 vectors: RhoA wild type, T19N dominant negative mutant, and G14V constitutively active mutant.

EP Reagent Phosphomolybdotungstic Reagent - 100ML

1065000 100ML
EUR 226.8

F8 Over-expression Lysate Product

GWB-4223CC 0.1 mg Ask for price

AR Over-expression Lysate Product

GWB-524326 0.1 mg Ask for price

MB Over-expression Lysate Product

GWB-543EE8 0.1 mg Ask for price

C5 Over-expression Lysate Product

GWB-611C50 0.1 mg Ask for price

F7 Over-expression Lysate Product

GWB-2B9655 0.1 mg Ask for price

HP Over-expression Lysate Product

GWB-19D90B 0.1 mg Ask for price

C9 Over-expression Lysate Product

GWB-A98C50 0.1 mg Ask for price

GK Over-expression Lysate Product

GWB-ABEC99 0.1 mg Ask for price

C6 Over-expression Lysate Product

GWB-4CD0B5 0.1 mg Ask for price

T Over-expression Lysate Product

GWB-4D17A7 0.1 mg Ask for price

C2 Over-expression Lysate Product

GWB-69AF56 0.1 mg Ask for price

C7 Over-expression Lysate Product

GWB-6F310B 0.1 mg Ask for price

GC Over-expression Lysate Product

GWB-6FD425 0.1 mg Ask for price

F2 Over-expression Lysate Product

GWB-74B4A0 0.1 mg Ask for price

GK Over-expression Lysate Product

GWB-799C20 0.1 mg Ask for price

F9 Over-expression Lysate Product

GWB-7A1142 0.1 mg Ask for price

TF Over-expression Lysate Product

GWB-FDE7E0 0.1 mg Ask for price

FH Over-expression Lysate Product

GWB-B00EEC 0.1 mg Ask for price

KL Over-expression Lysate Product

GWB-EF6FA2 0.1 mg Ask for price

MB Over-expression Lysate Product

GWB-DDB100 0.1 mg Ask for price

XG Over-expression Lysate Product

GWB-C19FF5 0.1 mg Ask for price

PC Over-expression Lysate Product

GWB-C40C56 0.1 mg Ask for price

AVIDIN/BIOTIN BLOCKING REAGENT Reagent

GWB-Q00289 30 ml Ask for price

Cdc42 Expression Vector Set

STA-455 1 kit
EUR 1765.2
Description: Cdc42 Expression Vector Set contains 3 vectors: Cdc42 wild type, T17N dominant negative mutant, and Q61L constitutively active mutant.

OPN expression inhibitor 1

T62820-10mg 10mg Ask for price
Description: OPN expression inhibitor 1

OPN expression inhibitor 1

T62820-1g 1g Ask for price
Description: OPN expression inhibitor 1

OPN expression inhibitor 1

T62820-1mg 1mg Ask for price
Description: OPN expression inhibitor 1

OPN expression inhibitor 1

T62820-50mg 50mg Ask for price
Description: OPN expression inhibitor 1

OPN expression inhibitor 1

T62820-5mg 5mg Ask for price
Description: OPN expression inhibitor 1

CRX Over-expression Lysate Product

GWB-372B50 0.1 mg Ask for price

FST Over-expression Lysate Product

GWB-3758FE 0.1 mg Ask for price

PNN Over-expression Lysate Product

GWB-379ABB 0.1 mg Ask for price

CRK Over-expression Lysate Product

GWB-37B7E4 0.1 mg Ask for price

B2M Over-expression Lysate Product

GWB-39B4E3 0.1 mg Ask for price

NGB Over-expression Lysate Product

GWB-39F54D 0.1 mg Ask for price

KIN Over-expression Lysate Product

GWB-3ABEBE 0.1 mg Ask for price

OXT Over-expression Lysate Product

GWB-3B1FD3 0.1 mg Ask for price

PXK Over-expression Lysate Product

GWB-3C8EA1 0.1 mg Ask for price

ALB Over-expression Lysate Product

GWB-3E03B0 0.1 mg Ask for price

IL9 Over-expression Lysate Product

GWB-3E3A84 0.1 mg Ask for price

HLA Over-expression Lysate Product

GWB-3E6FB0 0.1 mg Ask for price

SPR Over-expression Lysate Product

GWB-3FACD1 0.1 mg Ask for price

SPN Over-expression Lysate Product

GWB-404D95 0.1 mg Ask for price

AIP Over-expression Lysate Product

GWB-40DF2C 0.1 mg Ask for price

CSK Over-expression Lysate Product

GWB-415B1A 0.1 mg Ask for price

WT1 Over-expression Lysate Product

GWB-41C1E8 0.1 mg Ask for price

C8B Over-expression Lysate Product

GWB-41E9AB 0.1 mg Ask for price

HDC Over-expression Lysate Product

GWB-4302B9 0.1 mg Ask for price

TNF Over-expression Lysate Product

GWB-448BBB 0.1 mg Ask for price

PNP Over-expression Lysate Product

GWB-4538EC 0.1 mg Ask for price

MUT Over-expression Lysate Product

GWB-455C37 0.1 mg Ask for price

CFP Over-expression Lysate Product

GWB-4575E9 0.1 mg Ask for price

HPN Over-expression Lysate Product

GWB-4602DE 0.1 mg Ask for price

C1D Over-expression Lysate Product

GWB-461FBD 0.1 mg Ask for price

PIP Over-expression Lysate Product

GWB-4782A0 0.1 mg Ask for price

SF1 Over-expression Lysate Product

GWB-47A9D3 0.1 mg Ask for price

DDO Over-expression Lysate Product

GWB-481A81 0.1 mg Ask for price

LYZ Over-expression Lysate Product

GWB-4830E7 0.1 mg Ask for price

PAM Over-expression Lysate Product

GWB-48AFF2 0.1 mg Ask for price

DCN Over-expression Lysate Product

GWB-4AB343 0.1 mg Ask for price

MVD Over-expression Lysate Product

GWB-4B1DAE 0.1 mg Ask for price

CPM Over-expression Lysate Product

GWB-4B1F3E 0.1 mg Ask for price

REN Over-expression Lysate Product

GWB-4B825B 0.1 mg Ask for price

HRK Over-expression Lysate Product

GWB-4BB955 0.1 mg Ask for price

SHD Over-expression Lysate Product

GWB-4BFEE6 0.1 mg Ask for price

GH1 Over-expression Lysate Product

GWB-4F3DD0 0.1 mg Ask for price

IVD Over-expression Lysate Product

GWB-4F555F 0.1 mg Ask for price

SLA Over-expression Lysate Product

GWB-4F6FFE 0.1 mg Ask for price

AK4 Over-expression Lysate Product

GWB-4FADC0 0.1 mg Ask for price

BRE Over-expression Lysate Product

GWB-4FC6EC 0.1 mg Ask for price

MOS Over-expression Lysate Product

GWB-503237 0.1 mg Ask for price

ERF Over-expression Lysate Product

GWB-5242BB 0.1 mg Ask for price

HFE Over-expression Lysate Product

GWB-5243B9 0.1 mg Ask for price

TEK Over-expression Lysate Product

GWB-533C4C 0.1 mg Ask for price

MIA Over-expression Lysate Product

GWB-534100 0.1 mg Ask for price

IDE Over-expression Lysate Product

GWB-5367D7 0.1 mg Ask for price

AFP Over-expression Lysate Product

GWB-536D51 0.1 mg Ask for price

RDX Over-expression Lysate Product

GWB-53CF80 0.1 mg Ask for price

ILK Over-expression Lysate Product

GWB-54E227 0.1 mg Ask for price

SFN Over-expression Lysate Product

GWB-55C5F7 0.1 mg Ask for price

BPI Over-expression Lysate Product

GWB-55FF0C 0.1 mg Ask for price

MAX Over-expression Lysate Product

GWB-56E43C 0.1 mg Ask for price

TAZ Over-expression Lysate Product

GWB-572853 0.1 mg Ask for price

MLN Over-expression Lysate Product

GWB-576AA3 0.1 mg Ask for price

CA2 Over-expression Lysate Product

GWB-578B82 0.1 mg Ask for price

GIP Over-expression Lysate Product

GWB-57B640 0.1 mg Ask for price

MKX Over-expression Lysate Product

GWB-57FD34 0.1 mg Ask for price

FAS Over-expression Lysate Product

GWB-586DE6 0.1 mg Ask for price

ADK Over-expression Lysate Product

GWB-590E04 0.1 mg Ask for price

CAT Over-expression Lysate Product

GWB-59B4AF 0.1 mg Ask for price

AES Over-expression Lysate Product

GWB-5A4211 0.1 mg Ask for price

GRP Over-expression Lysate Product

GWB-5A56CC 0.1 mg Ask for price

C8A Over-expression Lysate Product

GWB-5AD920 0.1 mg Ask for price

ME2 Over-expression Lysate Product

GWB-5B40C3 0.1 mg Ask for price

TTK Over-expression Lysate Product

GWB-5B4DBF 0.1 mg Ask for price

HGF Over-expression Lysate Product

GWB-5CC3A0 0.1 mg Ask for price

XDH Over-expression Lysate Product

GWB-5CD953 0.1 mg Ask for price

DES Over-expression Lysate Product

GWB-5E571D 0.1 mg Ask for price

LOX Over-expression Lysate Product

GWB-5FE87A 0.1 mg Ask for price

BMX Over-expression Lysate Product

GWB-603D44 0.1 mg Ask for price

GAA Over-expression Lysate Product

GWB-611DD0 0.1 mg Ask for price

DR1 Over-expression Lysate Product

GWB-62642D 0.1 mg Ask for price

ABR Over-expression Lysate Product

GWB-62B984 0.1 mg Ask for price

CA3 Over-expression Lysate Product

GWB-62F5B6 0.1 mg Ask for price

FUZ Over-expression Lysate Product

GWB-635D50 0.1 mg Ask for price

HGD Over-expression Lysate Product

GWB-64C9ED 0.1 mg Ask for price

JTB Over-expression Lysate Product

GWB-655583 0.1 mg Ask for price

FAH Over-expression Lysate Product

GWB-65575F 0.1 mg Ask for price

LPP Over-expression Lysate Product

GWB-1EE6BD 0.1 mg Ask for price

QKI Over-expression Lysate Product

GWB-2019C5 0.1 mg Ask for price

HBB Over-expression Lysate Product

GWB-2046D5 0.1 mg Ask for price

ZAK Over-expression Lysate Product

GWB-20AE0D 0.1 mg Ask for price

PF4 Over-expression Lysate Product

GWB-212C3B 0.1 mg Ask for price

TFG Over-expression Lysate Product

GWB-215F68 0.1 mg Ask for price

ACE Over-expression Lysate Product

GWB-21AE7F 0.1 mg Ask for price

ERH Over-expression Lysate Product

GWB-220D0B 0.1 mg Ask for price

GIF Over-expression Lysate Product

GWB-23C77E 0.1 mg Ask for price

PGD Over-expression Lysate Product

GWB-242ED0 0.1 mg Ask for price

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